How do you inject Xgeva?
The recommended dose of XGEVA is 120 mg administered once every 4 weeks, as a single injection under the skin (subcutaneous). XGEVA will be injected into your thigh, abdomen or upper arm. If you are being treated for giant cell tumour of bone, you will receive an additional dose 1 week and 2 weeks after the first dose.
Where is Xgeva given?
How to use Xgeva Vial. This medication is given by injection under your skin in the upper arm, upper thigh, or abdomen by a healthcare professional as directed by your doctor, usually every 4 weeks.
What does Xgeva do to your bones?
XGEVA® works to restore balance in your bones More signals to bone breakdown cells means that bone breakdown speeds up, which weakens bone and can lead to serious bone problems. In people with multiple myeloma, the bone breakdown and bone buildup are not balanced due to abnormal signals from cancer cells.
Does Xgeva cause back pain?
The most common adverse reactions in patients receiving XGEVA® for giant cell tumor of bone were arthralgia, headache, nausea, back pain, fatigue, and pain in extremity. The most common serious adverse reactions were osteonecrosis of the jaw and osteomyelitis.
How long can you stay on Xgeva?
Xgeva is given once every 4 weeks. For giant cell tumors and hypercalcemia caused by cancer, you’ll need extra doses on days 8 and 15. Prolia injections are given every 6 months.
Why is Xgeva given?
The Xgeva brand of denosumab is used to prevent bone fractures and other skeletal conditions in people with tumors that have spread to the bone. Xgeva is also used to treat giant cell bone tumor in adults and teenagers with fully matured bone structure.
What’s the difference between Prolia and Xgeva?
Denosumab is the generic name for the trade name drugs Prolia or Xgeva. In some cases, health care professionals may use the trade names Prolia or Xgeva when referring to the generic drug name denosumab. Prolia and Xgeva are the same generic drug (denosumab).
Does Xgeva stop bone metastasis?
Xgeva (denosumab) is a preventive medicine developed by Amgen to check the spread of cancer to the bones. It was approved by US Food and Drug Administration (FDA) as the first and only rank ligand inhibitor for the prevention of skeletal-related events (SREs) in patients with bone metastases from solid tumours in 2010.
When should I stop taking Xgeva?
Official Answer. Xgeva is meant to be taken long-term. However, Xgeva should be discontinued if you experience intolerable side effects or serious side effects such as osteonecrosis of the jaw or osteomyelitis, or if Xgeva appears to be ineffective for you.
Where is the left kidney located in the body?
Location. The left kidney is located slightly more superior than the right kidney due to the larger size of the liver on the right side of the body. Unlike the other abdominal organs, the kidneys lie behind the peritoneum that lines the abdominal cavity and are thus considered to be retroperitoneal organs.
Which side of the kidney is concave?
The kidneys are bean-shaped with the convex side of each organ located laterally and the concave side medial. The indentation on the concave side of the kidney, known as the renal hilus, provides a space for the renal artery, renal vein, and ureter to enter the kidney.
What is the center of the kidney called?
• Renal pelvis: This is the center of the kidney, and is fed from the major calyces. The renal pelvis then connects to the renal hilus, which drains the urine out into the ureter and eventually into the bladder to be eliminated from the body.
What is the anatomy of the kidneys?
The Anatomy of the Kidneys 1 Anatomy. Each person has two kidneys. 2 Function. The main purpose of the kidneys is to filter blood and maintain fluid and electrolyte balance in the body. 3 Associated Conditions. A number of diseases and conditions can impact the function of the kidneys. 4 Tests. 5 Treatment.