What is MicroRNA hsa-mir-25-3p?
MicroRNA hsa-miR-25-3p suppresses the expression and drug induction of CYP2B6 in human hepatocytes NCBI Skip to main content Skip to navigation Resources How To About NCBI Accesskeys My NCBISign in to NCBISign Out PMC US National Library of Medicine National Institutes of Health
Does HSA-mir-100-5p transfection enhance the invasion and motility of nescs?
Results: hsa-miR-100-5p transfection enhanced the invasion and motility of NESCs. After hsa-miR-100-5p transfection, mRNA expression of SWItch/sucrose non-fermentable-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 (SMARCD1) was significantly attenuated.
What is the mechanism of action of mir-630?
Cao JX, Lu Y, Qi JJ, An GS, Mao ZB, Jia HT, et al. MiR-630 inhibits proliferation by targeting CDC7 kinase, but maintains the apoptotic balance by targeting multiple modulators in human lung cancer A549 cells. Cell Death Dis. 2014;5:e1426.
Is has-mir-100-5p involved in the pathogenesis of endometriosis?
Background: A number of microRNAs are aberrantly expressed in endometriosis and are involved in its pathogenesis. Our previous study demonstrated that has-miR-100-5p expression is enhanced in human endometriotic cyst stromal cells (ECSCs). The present study aimed to elucidate the roles of has-miR-100-5p in the pathogenesis of endometriosis.
Does down-regulated HSA-mir-138-2-3p enhance radio-sensitivity under radiation?
According to the predicted genes and pathways of differential miRNAs target, down-regulated expression of hsa-miR-138-2-3p under radiation was thought to play a key role in enhancing the radio-sensitivity in human laryngeal squamous cancer stem cells.
Is HSA-mir-138-2-3p a potential biomarker for larynx cancer?
These results will be useful for a better understanding of the cell biology of hsa-miR-138-2-3p in laryngeal CSCs, and for serving hsa-miR-138-2-3p as a promising biomarker and as a target for diagnosis and for novel anti-cancer therapies for laryngeal cancers.
How does HSA-mir-25-3p interact with its cognate CYP2B6 target sequence?
Hsa-miR-25-3p regulates CYP2B6 directly by an Ago4 dependent manner RNA EMSAs were performed to explore whether hsa-miR-25-3p or hsa-miR-504-5p is able to interact with its cognate CYP2B6target sequence directly. As shown in Fig. 3A, hsa-miR-25-3p could bind its cognate CYP2B6mRNA oligonucleotide to form a complex (lane 6).
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